Medimmune Limited

"Human Papilloma Virus (HPV) has been implicated in a range of cancers. Currently, a prophylactic vaccine is prescribed for adolescent girls with a view to prevent infection by HPV. However, this preventative vaccine does not have a therapeutic effect on malignancies developed as a result of HPV infection. In this regard, the use of nucleic acid vaccines ...

Biopharmaceuticals (or biologics) are medicines that are made from biological materials, most usually proteins. The UK is a promininet stakeholder in this sector, which is growing in importance as biologics are often more specific to their target in the body and have fewer side effects. The development and production of biologics is, however, a labour and...

Sphere Fluidics Limited is an SME focusing on the development of novel, single cell analysis technologies. MedImmune, the global biopharmaceuticals arm of AstraZeneca, is a pioneer in biopharmaceutical discovery and development. Both companies have pooled their synergistic, science skills to propose the development of a unique, integrated microfluidic ins...

The treatment of some chronic diseases such as rheumatoid arthritis sometimes requires more than a typical tablet or ‘pill’ can deliver. A new generation of so-called ‘biopharmaceutical’ medicines includes substances which cannot be swallowed because they are destroyed in the stomach. These include ‘monoclonal antibodies’, or mAbs, which are injected subc...

The cost to patients and healthcare providers for Monoclonal Antibody (MAb) treaments has traditionally been high. The complex process required to generate, purify and formulate the drug add significantly to the overall cost. Although efforts have been made to reduce costs by looking at increasing manufacturing efficiencies e.g., selection of new chromato...

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