GSK PLC

To employ recent statistical innovations and introduce 'trial emulation' into the drug development process within pharmaceutical industry leader GSK to help design future research and accelerate access to drugs. Emulated trials use available data enabling faster exploration of hypotheses for new treatments without the need for a new clinical trial.

The project will deliver significant improvements in speed and quality of pharmaceutical product manufacturing processes. This will be achieved through an embedded understanding of the impact of pressure on polymorphs in active pharmaceutical ingredients (APIs), which impacts product stability and biopharmaceutics, ultimately resulting in increased profit...

Currently, there are no disease-modifying treatments that can prevent or slow down PD. PD, like other neurodegenerative conditions, is a disorder involving both genetic (e.g. _PINK1_ and _Parkin_ genes) and environmental factors (e.g. age, pesticides). Recently, multiple regions of PD patient's DNA were found to be different to those not having the diseas...

The project herein involves evaluating whether AI and other digital tools can improve understanding of how to progress tuberculosis science to mitigate its global burden. Tuberculosis is the leading global infectious threat and the poor are disproportionately affected. With the increasing burden of HIV-tuberculosis co-infections, tuberculosis has become a...

New therapeutic products in the pharma industries are invariably large, complex chemical molecules -- e.g., synthetic active ingredients, amino acids, peptides etc. In the consumer goods and food industries, complex emulsions form the backbone of products such as detergents, beauty products, milk and other liquid-based foods. An essential pre-requisite fo...

Public description Industrial Digital Technologies (IDT's) are disrupting industries across the globe. The breadth and depth of these changes herald the transformation of entire systems of production, management, and governance. There is overwhelming evidence that IDTs can provide a step change in industrial productivity(2). The Smart Connected Factory is...

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To transform both the depth and quality of consumer driven insights into brand perception, captured by the Shopper Science Laboratory, using a suite of novel interactive Augmented Reality technologies, leading to new product creation and a wider market share.

Awaiting Public Project Summary

"The London Medical Imaging & Artificial Intelligence Centre for Value-Based Healthcare will improve NHS patient care and health outcomes, reduce healthcare costs and support the growth of companies, supporting the economy. It will do this by applying artificial intelligence technologies to medical imaging (for example MRI scans, CT scans PET scans and ul...

Awaiting Public Project Summary

The project will develop a new, rapid and non-destructive test instrument for predicting tablet efficacy and performance, based on direct measurements of tablet porosity using terahertz light. In so doing, we expect to contribute to manufacturing efficiency improvements in production of advanced solid dose medicines. Our technology will initially be marke...