B G Research Limited

_To advance the novel CENOS medical device to the required Manufacturing Readiness Level to enable scaled production. CENOS enables the rapid, mobile detection of a range of significant animal and human diseases._

Project aim is to provide capability for early in-field direct testing of unprocessed biological samples e.g. swabs and blood for economically important veterinary pathogens, in this case screening swab samples taken from the beaks and cloaca of birds for detecting "bird flu". Initially we aim to support existing lab testing and ultimately explore the pot...

Project objective is to provide capability for early in-field direct testing of swabs and blood for economically important veterinary pathogens in, supporting existing lab testing. BGR have developed a novel method and instrument for performing sensitive in-field molecular diagnostic tests for the detection of viruses without the requirement for expert sc...

BG Research have a simplified method for testing patients for infections caused by viruses, the QuRapID-XF technology. Developed in response to the Ebola outbreak, it enables portable testing directly from patient samples. This removes the need for a lab or expert users -- important as it was designed to be used in resource poor environments in rural Afri...

BGR has developed a method for detecting viral pathogens directly from crude samples, removing the requirement for complex lab facilities or expert use. The technique was originally developed in the wake of the 2015 Ebola outbreak to establish if it is possible to perform laboratory standard molecular diagnostics in resource poor environments. The proposa...

BGR has developed a method for detecting viral pathogens directly from patients, removing the requirement for complex lab facilities or expert use. While human diagnostics has evolved, there has been little progress for testing animals for important pathogens. The UK foot and mouth disease outbreaks in 2001 cost the country over £3bn in losses to the agri...

The project investigates the feasibility of detecting bacterial infections, causing sepsis, directly from whole human blood. The process involves lysing the bacterial cells by rapid cyclical freezing and boiling followed by detection of the released nucleic acid by real-time PCR. This novel approach will enable detection of bacterial infection in the crit...

This project centres on the proof of concept of a simple, rapid diagnostic platform for the differentiation of viral haemorrhagic fevers in resource poor environments. The benefits of this approach; 1. Simplicity, requiring only a fingerprick of blood. 2. Reduced time to detection, from blood to result in around 30 mins. 3. Suited to resource poor environ...

This project will generate an optical detection system and associated software for true realtime determination of fluorescence levels generated during real-time PCR. BioGene (BG) has a technology platform capable of completing the real-time PCR process in 10 minutes and this speed combined with independent reaction control lends itself to a number of nove...

This project will produce and evaluate protype consumables suitable for the diagnostic separation and detection of DNA targets differing by only a single base pair in length. A large number of genetic tests rely on polymorphisms between DNA molecules, including DNA fingerprinting. The standard kits available on the marketplace involve the use of expert op...

BioGene, BG Research, and the University of Hull are working together to bring rapid, accurate testing for sepsis to the point of care. The system will identify not only the pathogen but also provide information on its antibitiotic sensitivity and in less than 1 hour, allowing the clinical team to correctly and rapidly treat the infection, saving both liv...

Recent increases in genomic information has led to an exponential increase in the numbers of genetic diseases characterised. This and a greater understanding of the infection process, generates the need to detect larger numbers of targets such as pathogens and disease causing genetic variants as rapidly as possible and in a single test. One such approach ...