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Company profile

Hypha Discovery Limited

Hypha Discovery - Experts in metabolite synthesis, purification and MetID

Hypha Discovery is a trusted CRO with expertise in metabolite synthesis, purification, structure elucidation and natural products.

CRN
05148143
Founded
2004
Age
22

Overview

Legal name
HYPHA DISCOVERY LIMITED
Region
South East England
Registered address
154B BROOK DRIVE
MILTON PARK
ABINGDON
ENGLAND
OX14 4SD
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

6 events
31 Mar
2027

Accounts due

Accounts Due

Next accounts due date

22 Jun
2026

Confirmation statement due

Confirmation Due

Next confirmation statement due date

08 Jun
2026

Confirmation Statement With No Updates

Confirmation-statement

CS01 | Transaction MzUyNTg0NDY1MmFkaXF6a2N4

Published 08 Jun 2026 07:20

30 Jun
2025

Accounts filed

Accounts

Last accounts made up date

08 Jun
2025

Confirmation statement filed

Confirmation

Last confirmation statement made up date

08 Jun
2004

Incorporated

Inception

Company registered at Companies House

Public funding

6 awards
First funded
2012
Funded years
2012, 2014, 2016, 2017, 2019, 2020
Age at first award
8 years

Projects

2020 Feasibility Studies Lead participant

From O to N: engineering the gap COVID-19 continuity

1 Jun 2020 to 30 Nov 2020

Awarded
£60,357
Total cost £60,357

no public description

2019 Feasibility Studies Lead participant

From O to N: engineering the gap

1 Apr 2019 to 31 Dec 2020

Awarded
£330,368
Total cost £471,954

"Metabolites of drugs often need to be investigated and tested as part of regulated safety assessments during drug development. _N_-glucuronides are a class of metabolites increasingly observed as a significant route of drug elimination and are most likely to exhibit transporter-mediated pharmacologic activity and drug-drug-interactions. However, _N_-gluc...

2017 Collaborative R&D Lead participant

PolyCYPs: optimising a preclinical platform tool to reduce pharmaceutical attrition rates

1 Jul 2017 to 30 Sep 2019

Awarded
£368,818
Total cost £526,883

The major healthcare imperatives are to deliver effective prevention and treatment of diseases. Whist pharmaceutical intervention in disease progress is effective in many cases, the use of medicines can also lead to adverse reactions resulting in the need for further medical intervention, compounding the cost of therapy. The aim of this project is to furt...

2016 Feasibility Studies Lead participant

Project title: Refining oxidative enzyme systems from talented microorganisms for industrial biocatalysis

1 Jan 2016 to 31 Dec 2016

Awarded
£87,412
Total cost £124,874

Microorganisms and their cytochrome P450 (CYP) oxidative enzymes can be used for production of drug and agrochemical metabolites, or to produce new derivatives of early-stage lead compounds with improved properties. Hypha Discovery’s panel of wild-type bacteria is highly effective in producing oxidized metabolites by whole-cell biotransformation but has l...

2014 Feasibility Studies Lead participant

Microbial Enzymatic Drug Modification to Improve Treatment Outcomes

1 Jun 2014 to 31 Aug 2015

Awarded
£127,535
Total cost £170,048

The major healthcare imperatives are to deliver effective prevention and treatment of diseases. Whist pharmaceutical intervention of disease progress is effective in many cases, the use of medicines can also lead to adverse reactions resulting in the need for further medical intervention, compounding the cost of therapy. The aim of this project is to furt...

2012 Feasibility Studies

Identifying novel brain active molecules: Developing an integrated bioengineering & in silico screening platform technology (IBIS)

1 Nov 2012 to 30 Sep 2013

Awarded
£59,635
Total cost £79,513

The major imperative of the pharmaceutical industry is to effectively translate insights gained from basic research into new medicines. This task is toughest for brain disorders such as Parkinson’s and Alzheimer’s disease. The WHO has indicated that this will become the major medical need of the 21st century. Brain drugs take longer to get to market and t...

Product types

Collaborative R&D Feasibility Studies