IHG Pharmaco Limited

The project builds on earlier Innovate funded feasibility work and comprises manufacturing a prototype test for validation and stability testing, for an eventual manufactured form of a novel test for adverse pregnancy outcomes affecting mothers and children. This will include Black and Asian ethnicity patients who are at higher risk of these adverse outco...

COVID19 has required face to face contact with patients to be as limited as possible thus making obtaining clinical trial samples very difficult. The project comprises using mouthswabs to gain access to patients DNA to genotype for the incidence of a biomarker associated with adverse birth outcomes and include the results in a large clinical study. These ...

The project comprises determining the feasibility of making a manufactured form of a diagnostic test that can utilise capillary electrophoresis to detect an important gene associated with human health.

"To develop the test, supplier to prototype the assay to run on the ABI analyser as follows: The assay probes to be fluorescently labelled to produce clearer and ‘cleaner’ images to maximise assay resolution.Optimise polymer for non-denaturing run conditions Extract DNA from saliva and quantify Run assay and DNA from saliva on a long capillary using capil...