Cellular Systems (Grantham) Limited

**This project addresses an identified environmental, healthcare and commercial demand for sustainable alternatives to single-use plastic personal protective equipment (PPE).** As part of the UK's COVID-19 response, the Department of Health and Social Care (DHSC) PPE strategy identifies a need for an additional 5 billion PPE items to address the increased...

**The project addresses an identified healthcare need and commercial demand for high-quality, sustainably-produced bioactive polyphenolic compounds.** Coronaviruses infect cells by binding to the angiotensin-converting-enzyme-2 (ACE2) membrane protein. This can be inhibited by polyphenols, specifically quercetin, increasing resistance to infection. Querce...

**BUSINESS NEED:** Materials derived from chitin (e.g. chitosans, chitooligosaccharides (COSs) and glucosamine) are of growing importance in biomedicine, cosmetics, healthcare, packaging and agriculture. Discussions with IVC Brunel, (the leading white-label supplier of supplements to UK supermarkets) and IVC Nutrition Corporation revealed that the: \* Sup...

**The project addresses an identified healthcare need and commercial demand for high-quality, sustainably-produced bioactive polyphenolic compounds.** Development of products derived from fruit and vegetables can support the recovery of individuals by enhancing their immune response, leading to faster recovery time or weakening future reinfection by mutat...

Tomato growers in the UK need to detect Botrytis cinerea/grey mould early in it's development to avoid economic loss. Botrytis impacts both productivity and profitability of the industry year long, with backgrounds of 1- 10% of plants infected throughout the year, reaching 30% at the year end. The aim of this project is to investigate the feasibility of e...

Molecularly Imprinted Polymers (MIPs) have been proven for a range of applications including affinity purification. MIP Diagnostics using a revolutionary manufacturing process have developed nano-MIPs. This proprietary method enables much more refined MIPs based products including affinity chromatography media for separation of high value compounds. This ...

Necrotic Enteritis (NE) is a widespread problem with poultry gut health, leading to losses in the global Poultry industry of over £3bn, a burden of £25-30 million in the UK. We are developing a monitor that will indicate when the poultry are developing this problem in their guts, allowing farmers to take early and effective action, with non-antibiotic int...

This project is designed to test the feasibility of using e-nose technology as a real time monitoring tool for changes in poultry Gastro-Intestinal Tract (GIT) microflora, specifically Clostridium Perfringens (CP) - the causative bacterium of Necrotic Enteritis (NE). NE can have a dramatic impact on poultry growth and mortality, compromising both animal w...

Campylobacter is an issue affecting the UK’s general population and its food and agricultural industries. Over the past 5- 10 years much effort has been made by the government to address the problem, however it still causes 100+ deaths, 22,000 hospitalisations and over 280,000 reported cases a year. In November, 2014 the Food Standards Agency (FSA) reveal...

Early stage detection of infectious agents in livestock destined for the human food supply chain includes tuberculosis, campylobacter, E coli, avian influenza and micro-organisms that cause mastitis. The agents cause diseases that cost UK and global agriculture billions of pounds every year. This TSB project will manufacture a new diagnostic platform, com...

Egg shell waste amounts to 15,000 tonnes per annum in the UK, it is predominantly sent to land fill. This is both bad for the environment and also costs the egg processors hard earned cash. This material, comprising a mineral calcium carbonate and a biological component, proteins and bioactive molecules, has a value. The mineral, at commodity prices, coul...

Control of food poisoning from Campylobacter, using soil inhabiting bacteria.