Company profile
Xenogesis Limited
XenoGesis is now part of Sygnature Discovery
XenoGesis is now part of Sygnature Discovery. Find us at sygnaturediscovery.com.
Corporate ownership
Updated 06 Jun 2026 16:52
Company events
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Published 16 Apr 2026 17:59
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Published 16 Apr 2026 17:57
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Published 16 Apr 2026 17:56
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Incorporated
InceptionCompany registered at Companies House
Public funding
Projects
Development and validation of a dynamic drug screening platform for ADME testing .
1 Oct 2014 to 30 Jun 2016
The Caco-2 cell line is the gold standard for the prediction of drug absorption and permeability in vitro by mimicking the small intestine. However, this model lacks the dynamic motion which represents one of the physiological functions of the small intestine (peristalsis). In our research, we investigate the possibility the similarity between the static ...
3D cell culture model for studying Non-Alcoholic Fatty Liver Disease (NAFLD).
1 Sep 2014 to 30 Nov 2015
Non-alcoholic fatty liver disease (NAFLD) encompasses a range of conditions from fatty liver (steatosis) to non-alcoholic steatohepatitis (NASH). NAFLD is a condition affecting around 30 % of the general population and 70 % of obese and diabetic patients. The prevalence of NAFLD is set to rise as the obesity and diabetic pandemic escalates. It is therefor...
Evaluation of membrane-retentive pro-drugs to increase duration of effect to enable once-a-day dosing of inhaled muscarinic M3 receptor antagonists
1 Apr 2013 to 30 Jun 2014
Inhalation is an increasingly important delivery approach of therapeutic agents to the lung. There remains an unmet medical, commercial and practical need for 'once-a-day' treatment in various therapeutic areas and this is lacking for some current therapies. Once daily treatment is possible in some cases, but this approach can involve over-dosing to give ...