Company profile
Mission Therapeutics Limited
Mission Therapeutics Deubiquitylating enzymes: multiple drug opportunities across therapeutic areas
Mission Therapeutics Limited is a UK company with status active founded in 2011 based in East of England.
Company events
Reference milestones and recent Companies House filing stream events.
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Published 02 Jul 2026 10:56
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Published 26 Nov 2024 01:25
Incorporated
InceptionCompany registered at Companies House
Public funding
Projects
Development of USP7 inhibitors for cancer therapy
1 Oct 2015 to 30 Sep 2017
MISSION Therapeutics, a UK-based SME is a world-leading expert in deubiquitylating enzyme (DUB) drug discovery, with a number of projects in lead optimisation. Through counter-screening our ongoing projects, we identified a small molecule inhibtiors of a DUB drug target with potential to be developed for treating soft tissue sarcomas and other cancers wit...
Feasibility of inhibiting desumoylating enzymes for treating platinum-resistant cancers
1 Aug 2014 to 31 Jul 2015
Through work funded by the TSB, MISSION Therapeutics identified SENP enzymes as new therapeutic targets for treating drug-resistant ovarian cancer. For drug discovery, SENPs pose a distinct challenge as they require specific substrates and assays and they are not well studied in terms of their biological role(s). For these reasons, SENPS are currently con...
Identifying deubiquitylating enzymes (DUBs) as targets for treating of platinum-resistant ovarian cancer
1 Apr 2013 to 31 Mar 2014
Novel therapies tailored for treatment of platinum-resistant ovarian cancer is an area of clear unmet need. Ovarian cancer is responsible for more deaths per year than any other cancer of the female reproductive system and developing drug resistance remains the main limitation of current chemotherapies. We propose an innovative approach to identifying nov...