Autolus Limited

Immune cells such as T cells can be harvested from a patient's blood and genetically engineered to recognize and destroy cancer cells. This kind of immune therapy, which includes CAR T cell therapy is proving to be highly effective in treating cancers which have become resistant to chemotherapy and radiotherapy. There are currently six such engineered imm...

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Autolus are working to leverage existing expertise in antibody binder technology. We have designed a series of molecules that have the potential to lower viral load in patients, which is expected to reduce disease severity and lower the likelihood of developing symptoms that result in hospitalisation. The goal of the project is to evaluate the technical f...

Advanced Therapies have come of age. The spectacular clinical results demonstrated by novel gene-engineered T-cell therapies, with subsequent regulatory approvals in the US and EU, have confirmed the commercial reality of a new class of therapeutics that offer real hope to patients who are bereft of effective treatment options. But behind this hope lies a...

"**Advance Therapy Medicinal Products (ATMPs)** **are a new generation of treatments which use patients' cells as 'drugs' to treat a variety of diseases.** Although encouraging results have been reported, this technology is complex, expensive and currently only available to small numbers of patients. In **2018** the **UK** have formed **a network of three...

"The Northern Alliance Advanced Therapies Treatment Centre (NAATTC) is a group of NHS hospitals and services. NAATTC has a wide geographical reach across Scotland and the North of England and is responsible for the health care of 15 million NHS patients. Advanced therapies are becoming increasingly available with a growing number of companies developing t...

"Advanced Therapies have come of age. The spectacular clinical results demonstrated by novel gene-engineered T-cell therapies, with subsequent regulatory approvals in the US, have confirmed the commercial reality of a new class of therapeutics that offer real hope to patients who are bereft of effective treatment options. But behind this hope lies a deep ...

Chimeric Antigen Receptor therapies (CAR-T), represent an entirely new, potentially transformative approach to treating cancer. They combine the precision of a monoclonal antibody with the potency and persistence of the human immune system. Researchers in the USA have recently reported clinical data using CAR-T in blood cancers which are causing great exc...

T-cells are immune cells in our bodies whose function is to "seek and destroy" cells which are infected by viruses. Since T-cells actively move around our bodies looking for infected cells, medical science has long tried to make these T-cells attack cancer cells. Because cancer cells usually come from normal cells in our bodies without virus infections, T...

Multiple Myeloma (MM) is a cancer of a type of white blood cell called a plasma cell. MM is a disease of older people. Patients with MM develop bone fractures, pain, infections and kidney failure due to this cancer. Although it can be controled for a period, MM is currently incurable. T-cells are the part of our immune system which directly kill infected ...