Company Active LTD

Company profile

Freeline Therapeutics Limited

Freeline changing lives by innovative gene therapies

A leading biotechnology company focused on innovative liver directed gene therapies for bleeding disorders and other debilitating, chronic diseases

CRN
09500073
Founded
2015
Age
11

Overview

Legal name
SPUR THERAPEUTICS LIMITED
Region
East of England
Registered address
SYCAMORE HOUSE
GUNNELS WOOD ROAD
STEVENAGE
HERTFORDSHIRE
ENGLAND
SG1 2BP
Insolvency history
No

Corporate ownership

Updated 06 Jun 2026 16:52

2 levels 1 ultimate controller
1
Company Active LTD
Freeline Therapeutics Limited
CRN 09500073
2
Direct controller Active LTD
Bidco 1354 Limited
CRN 15295548
3
Ultimate controller
00055514
CRN 00055514

Company events

Reference milestones and recent Companies House filing stream events.

15 events
02 Apr
2027

Confirmation statement due

Confirmation Due

Next confirmation statement due date

30 Sep
2026

Accounts due

Accounts Due

Next accounts due date

03 Jul
2026

Change Person Director Company With Change Date

Officers

CH01 | Transaction MzUzMDM1NTg1M2FkaXF6a2N4

Published 03 Jul 2026 16:17

03 Jul
2026

Change Person Director Company With Change Date

Officers

CH01 | Transaction MzUzMDM1NTc1OWFkaXF6a2N4

Published 03 Jul 2026 16:15

03 Jul
2026

Change Person Director Company With Change Date

Officers

CH01 | Transaction MzUzMDM1NTY5NWFkaXF6a2N4

Published 03 Jul 2026 16:14

28 Mar
2026

Confirmation Statement With Updates

Confirmation-statement

CS01 | Transaction MzUxMjc2MzQyMGFkaXF6a2N4

Published 28 Mar 2026 13:03

26 Mar
2026

Cessation Of A Person With Significant Control

Persons-with-significant-control

PSC07 | Transaction MzUxMjc2MTM2M2FkaXF6a2N4

Published 26 Mar 2026 12:14

26 Mar
2026

Notification Of A Person With Significant Control

Persons-with-significant-control

PSC02 | Transaction MzUxMjc2MTI2NWFkaXF6a2N4

Published 26 Mar 2026 12:13

19 Mar
2026

Confirmation statement filed

Confirmation

Last confirmation statement made up date

31 Dec
2024

Accounts filed

Accounts

Last accounts made up date

27 Sep
2024

Certificate Change Of Name Company

Change-of-name

CERTNM | Transaction MzQzNzU1MTI3NWFkaXF6a2N4

Published 27 Sep 2024 03:23

27 Aug
2024

Mortgage Satisfy Charge Full

Mortgage

MR04 | Transaction MzQzMzQ5NzIzOGFkaXF6a2N4

Published 27 Aug 2024 17:14

22 Aug
2024

Mortgage Satisfy Charge Full

Mortgage

MR04 | Transaction MzQzMzEzMjQ5NGFkaXF6a2N4

Published 22 Aug 2024 17:41

22 Aug
2024

Mortgage Satisfy Charge Full

Mortgage

MR04 | Transaction MzQzMzEzMjQ4NGFkaXF6a2N4

Published 22 Aug 2024 17:40

19 Mar
2015

Incorporated

Inception

Company registered at Companies House

Public funding

5 awards
First funded
2017
Funded years
2017, 2018, 2019, 2020
Age at first award
2 years

Projects

2020 Knowledge Transfer Partnership

University of Leeds and Freeline Therapeutics Limited

1 Feb 2020 to 31 Aug 2023

Awarded
Unknown

To introduce advanced computational techniques and develop a new platform to accelerate discovery of novel and effective gene therapies to treat currently incurable diseases. To deliver new treatments faster and in a cost-effective manner.

2019 Collaborative R&D Lead participant

Using adeno-associated virus gene therapy to treat rare kidney disease

1 Feb 2019 to 31 Mar 2022

Awarded
£938,666
Total cost £1,564,444

Freeline is requesting a change of scope to project number 104902 – “Using AAV gene therapy to treat rare kidney disease” that would redistribute funds to enable critical safety risk mitigation experiments to be performed within the timelines of the grant.

2018 Collaborative R&D Lead participant

Development of an Innovative Supply Chain Model to Expedite Delivery of Viral Vector ATIMPs to Clinical Trials

1 Nov 2018 to 31 Oct 2021

Awarded
£297,645
Total cost £496,075

"The rapid development of novel treatments called Advanced Therapies, such as cell therapies and gene therapies have required new manufacturing facilities and technologies worldwide. Manufacturing of gene therapy viral vectors for human use requires specialised high-quality manufacturing facilities and there is currently insufficient such capacity in the ...

2018 Collaborative R&D

A shared scalable suspension platform for cost effective manufacture of novel AAV gene therapies

1 Nov 2018 to 31 Jan 2021

Awarded
£234,243
Total cost £390,406

"The rapid development of Gene Therapy Medicinal Products (GTMPs) requires new manufacturing processes and facilities. Gyroscope Therapeutics Ltd and Freeline Therapeutics Ltd are UK-based SMEs developing gene therapies for different indications but which are both delivered via adeno-associated viral (AAV) vectors. Gyroscope and Freeline intend to co-deve...

2017 Collaborative R&D Lead participant

Establishing Freeline Commercial Scale Viral Gene Therapy Manufacture for Fabry Disease

1 Dec 2017 to 31 Jan 2020

Awarded
£979,886
Total cost £1,399,837

The rapid development of novel treatments called Advanced Therapies, such as gene therapies that provide the correct proteins, have required new, manufacturing facilities worldwide. Freeline Therapeutics Limited (Freeline), a UK company that makes gene therapies to treat bleeding and metabolic disorders, will work with the Cell and Gene Therapy Catapult (...

Product types

Collaborative R&D Knowledge Transfer Partnership