Emergex Vaccines Holding Limited

The project proposes to advance a CD8 T-cell priming Chikungunya virus (CHIKV) vaccine candidate (PepGNP-ChikV) through preclinical development, cGMP manufacture and and MHRA regulatory submission for a Phase-1 clinical trial in the UK. The overall aim of this project is be ready to move into a Phase-1 clinical trial within 3 to 6 months of completion of ...

Chikungunya virus (CHIKV) imparts a high public health burden with more than a billion people living in endemic areas. CHICKV infection is spread to people by the bite of an infected mosquito. It is not often fatal but is very debilitating, with the potential for mother to child transmission. CHIKV. Outbreaks have occurred in countries in Africa, Asia, th...

"Influenza pandemics have been a recurrent health event through-out history. The infamous Spanish Flu of 1918, resulted in up to 100 million deaths - 5% of the world population. The most recent international pandemic took the shape of H1N1 virus in 2009\. The virulent H3N2 strain that resulted in \>225,000 infections in Australia is currently making a par...

From mosquito borne viruses such as Zika, to human-to-human transmitted viruses such as Ebola, the risk of infectious disease remains a true medical challenge for the world. Developing countries are disproportionately affected; nearly all the victims in the recent Ebola epidemic lived in low income African countries while Zika continues to spread to the r...