Company profile
Diosynvax LTD.
Vaccine Antigen Design | DIOSynVax | Cambridge
DIOSynVax: Achieving dramatic improvements to how we protect humanity against deadly pathogens. Discover advanced solutions to vaccine antigen design.
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MiscellaneousRP01SH01 | Transaction MzUxMDU1NjcxOWFkaXF6a2N4
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Incorporated
InceptionCompany registered at Companies House
Public funding
Projects
A Broadly Protective, Thermostable and Rapidly Deployable Pre-Pandemic pan-H5Nx Influenza Vaccine with mucosal delivery potential
1 Apr 2025 to 31 Mar 2027
The global spread of H5Nx influenza, with nearly 900 reported human cases and a fatality rate exceeding 50% in major strains, underscores the urgent need for innovative vaccine solutions. The diversity of H5Nx clades causing outbreaks reveals our inability to predict which strain from which clade might become pandemic. This situation exposes the limitatio...
Clinical development of DIOS-HFVac3: A pre-clinically effective multivalent vaccine for Lassa fever virus, Marburg virus, and Sudan ebolavirus
1 Oct 2023 to 30 Jun 2025
DIOSynVax, a clinical-stage biotechnology company based in Cambridge, UK, is working on a groundbreaking project to develop a novel vaccine against four diseases which cause outbreaks of high consequence to human health including Ebola, Lassa, Marburg and mpox . The primary goal of our project is to protect populations in low and middle-income countries (...
HFVac4: A Quadrivalent Viral Haemorrhagic Fever Vaccine for Africa
1 Apr 2022 to 31 Mar 2023
We have developed a pre-clinical trivalent Haemorrhagic Fever Vaccine (HFV) candidate able to combat three important African haemorrhagic fever viruses: Lassa Fever virus (LASV), Ebola (EBOV) and Marburg (MARV) viruses. Separately, a fourth vaccine monovalent candidate against Crimean-Congo Haemorrhagic Fever (CCHF) has been developed by our collaborator ...
DIOS-CoVax clinical trial recruitment and analysis
1 Dec 2021 to 31 Jan 2022
Vaccines that protect against multiple related viruses have been developed using DIOSynVax technology. This broadly protective approach is needed for the Coronaviruses such as SARS-COV-2 and SARS-COV, two of numerous related viruses that have the potential to cause future outbreaks from zoonotic reservoirs. We have designed antigens to induce an immune re...
DIOS-CoVax - A vaccine designed to protect against COVID-19 and future Coronavirus epidemics, mitigating antibody enhanced disease.
1 Sep 2020 to 31 Dec 2022
Safe and highly effective vaccines are the most promising medical interventions for the prevention of infectious diseases. At the time of writing, there have been over 5 million cases and 330,000 deaths reported to the WHO. The coronavirus, referred to as SARS-CoV-2, causes a respiratory disease termed COVID-19\. Current experimental Spike-based coronavir...
Digital Immune Optimized and Selected Pan-Influenza Vaccine Antigens ‘DIOS-PIVa’
1 Jun 2020 to 31 Mar 2021
no public description
Digital Immune Optimized and Selected Pan-Influenza Vaccine Antigens (DIOS-PIVa)
1 Apr 2019 to 31 Dec 2022
"There has never been a greater need for better influenza (Flu) vaccines to replace traditionally produced seasonal Flu vaccines that generate variable levels of protection. Seasonal Flu vaccines are imperfect and fail from time to time resulting in huge economic costs to the NHS and other national health services in this country and globally, when they f...