Company profile
Exactmer We build polymers from the ground up
Exactmer Limited is a UK company with status active founded in 2017 based in Yorkshire and the Humber.
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SH01 | Transaction MzUyNTc5NDA2NmFkaXF6a2N4
Published 07 Jun 2026 14:27
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Published 19 Sep 2024 08:45
Company registered at Companies House
Exactmer is a start-up dedicated to producing precision polymeric molecules with our patented Nanostar Sieving Technology. Using this disruptive new platform, we are creating exquisite synthetic and biological polymers, including oligonucleotides and mono-disperse polyethylene glycols (PEGs), ADC linkers, peptides and moremost of them bound for use in medicines that enhance patient quality of life.
Exactmer manufactures polymers designed to be purer than traditional polymers, for use in medicines.
Exactmer owns the Nanostar Sieving technology platform. This employs iterative liquid phase chemistry coupled to membrane purification to create polymers of outstanding purity. Exactmer currently supplies unimolecular polyethylene glycols (PEGS) up to 5kDa, and is exploring the production of oligonucleotides and peptides.
Exactmer has entered into a multi-million pound collaboration with GSK, AZ and Alnylam led by MMIC/CPI to develop and scale up the manufacture of therapeutic oligonucleotides using liquid phase synthesis.
A number of NDA contracts to explore the nanostar sieving technology for oligonucleotide synthesis.
1 Apr 2024 to 31 Mar 2026
The oligonucleotide synthesis landscape is undergoing a transformative shift, and Exactmer, in collaboration with the University of Manchester and Imperial College, is at the forefront with the Sustainable bioprocess for oligonucleotide manufacture using NanostarSieving (BioNanostar) project. Oligonucleotide-based therapeutics, face hurdles in manufacturi...
1 Jun 2023 to 31 May 2025
Oligonucleotides (oligos) are sequences of nucleotides monomers which usually contain between 15-25 nucleotides/ nucleotide-analogues, they offer promising treatment for a wide range of medical conditions. There are now 15 oligo drugs which have been approved between the EMA and FDA. In recent years, an **increasing number of oligos in clinical trials** h...
1 Jan 2023 to 31 Dec 2024
no public description
1 Jan 2023 to 30 Apr 2024
Polymers are long molecules, comprising repeated chemical units known as monomers. Polyethylene glycol (PEG), comprising ethylene glycol (EG) monomers, is a polymer widely used in biomedicine. PEG is used to improve the water-solubility of drugs and proteins, and to regulate their transport and retention in the body. However, the current EG monomers that ...
1 Nov 2020 to 31 Mar 2022
Polymers are long molecules comprising repeated chemical units known as monomers. Some polymers, such as polyethylene glycol (PEG), comprising ethylene glycol (Eg) monomers, are very useful parts of sophisticated nanomedicines, because they regulate the way that a medicine is transported around and retained in the body. Other polymers, including oligonucl...
1 Oct 2020 to 30 Jun 2021
Polymers are long molecules comprising repeated chemical units known as monomers. Some polymers, such as polyethylene glycol (PEG), comprising ethylene glycol (Eg) monomers, are very useful parts of sophisticated nanomedicines, because they regulate the way that a medicine is transported around and retained in the body. Chemically modified oligonucleotide...
1 Jun 2020 to 30 Nov 2020
no public description
1 Jun 2019 to 31 Aug 2020
"Polymers are long molecules comprising repeated chemical units known as monomers. Some polymers, such as polyethylene glycol (PEG), which comprises ethylene glycol (EG) monomers, are very useful as therapeutic agents and as parts of sophisticated nanomedicines, because they regulate the way that a medicine is transported around and retained in the body. ...
