Company profile
Hydregen Limited
HydRegen
Cleaner, safer, more efficient chemical manufacture. A spinout from the University of Oxford, commercialising a novel biotechnology. Our slot in technologies allow you to replace your heavy metal catalyst for hydrogenation reactions, or decarbonise existing redox biocatalysis processes all whilst operating within existing flow hydrogenation reactors.
Corporate ownership
Updated 07 Jul 2026 09:49
Latest accounts
Financial period: 1 Jan 2024 to 31 Dec 2024
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Incorporated
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Spinout profile
Company description
HydRegen develops technology that enables companies to synthesise chemicals faster and at a lower cost.
HydRegen's biotechnology platform offers cleaner, safer, faster chemical manufacture, blending exquisite precision with efficient processing. HydRegen is a spin out of the University of Oxford, and holds an exclusive licence to a patent protecting a novel biotechnology (patent number: WO2013050760 A2, granted in EU and US). Our goal is to enable customers in the chemicals sector to replace toxic heavy metals, decarbonise biocatalysis and speed up adoption of flow processes. We will achieve this by: • selling R&D scale products that lower the barrier-to-entry for biocatalysis, • carrying out contract research for sale of tailored products, and • offering packages of product sales, contract research and technology licences for commercial processes We have secured £420k (Innovate UK and University Seed Challenge Fund) for 18 months of industrial research and development. We expect to launch our first commercial product within our first year, and to enter our first commercial licencing deal within 18 months.
Project impact
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Public funding
Projects
Bio2Amine: Scaling cost-competitive paracetamol production
17 Oct 2025 to 17 Oct 2028
HydRegen is an early stage life-science start up committed to delivering next-generation manufacturing technologies that bridge between chemistry and biology, to fast-track cost and carbon competitive process that meet safety and sustainability requirements for UK manufacturing. Our technologies deliver 40% cost and 3xCO2e savings for manufacturing of che...
Bio2Amine-Fampridine: delivering sustainable small molecule API manufacturing
1 Feb 2025 to 31 Jul 2026
HydRegen is an early stage life-science start up committed to delivering next-generation manufacturing technologies that bridge between chemistry and biology, to fast-track cost and carbon competitive process that meet safety and sustainability requirements for UK manufacturing. Drochaid is a well-established industry specialist in catalyst screening, tes...
Tungsten Biocatalysis - Heavy Metal Enzymes for Sustainable Industrial Biocatalysis
1 Feb 2024 to 31 Jan 2028
Europe needs a sustainable chemical industry which will only be realized by new breakthrough technologies. Industrial biotechnology is established in chemical manufacturing, offering more efficient, more specific, safer and less energy demanding production, but is held back by the limited number of enzyme classes in industrial use. This project opens up a...
Biocatalytic nitro-reductions in scalable continuous flow reactors: paracetamol case study
1 Oct 2023 to 30 Sep 2025
**HydRegen vision:** The HydRegen technologies offer the potential for cleaner, safer, faster and cheaper chemical manufacture. Deep understanding of biology and chemistry allow the HydRegen team to select the best components from biology and use them to develop robust biotechnologies that solve real problems in the chemicals sectors. We expect our techno...
Intensification of metallo-enzyme production to unlock sustainable biocatalytic hydrogenation
1 Jul 2023 to 31 Dec 2023
**HydRegen** is a 2021 spin-out from the University of Oxford's Department of Chemistry. **Our vision:** The HydRegen technologies offer the potential for cleaner, safer, faster and cheaper chemical manufacture. Deep understanding of biology and chemistry allow the HydRegen team to select the best components from biology and use them to develop robust bio...
Unlocking biocatalytic hydrogenation for bulk chemical manufacture
1 Jan 2022 to 31 Dec 2023
**HydRegen** is a 2021 spin-out from the University of Oxford's Department of Chemistry. **Our vision:** The HydRegen technologies offer the potential for cleaner, safer, faster and cheaper chemical manufacture. We expect our technologies to play a part in the UK chemicals sector meeting ambitious Net Zero emissions targets (by 2050) and increasing adopti...
HydRegen: a sustainable chemistry platform
1 Feb 2021 to 31 Jul 2022
We have developed sustainable technologies that address unmet needs in the chemicals sector through academic research at the University of Oxford. Chemicals companies are interested in our technologies because they remove the need for toxic reagents, minimise the production of carbon-based waste products and lower energy demands compared to existing manuf...