Company profile
Thirtyfivebio Limited
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Applying specialist knowledge to develop small molecule antagonists of genetically-validated GPCR GPR35.
Corporate ownership
Updated 06 Jun 2026 16:52
Latest accounts
Financial period: 1 Jan 2024 to 31 Dec 2024
Company events
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CapitalSH01 | Transaction MzUyNTMzMzE0NWFkaXF6a2N4 | Paper/PDF filed
Published 09 Jun 2026 22:53
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Published 29 May 2026 01:02
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Published 24 Sep 2024 02:34
Incorporated
InceptionCompany registered at Companies House
Public funding
Projects
Precision Medicine Approach and Enhanced Patient Stratification for Ulcerative Colitis and Colorectal Cancer via GPR35 inhibition
1 Jun 2024 to 30 Nov 2025
ThirtyFiveBio has developed a world-leading understanding of how GPR35-signalling promotes gastrointestinal inflammatory metaplasia and cancer disease biology. In recent years, immunotherapy agents, such as checkpoint inhibitors, have led to dramatic survival benefits in some cancer patients. However, the majority of patients still do not respond adequate...
Enabling translational studies and clinical entry plan in gastro-intestinal inflammatory diseases and cancers for human GPR35 antagonist lead molecules.
1 Sep 2023 to 31 Aug 2024
ThirtyFiveBio has developed a world-leading understanding of how GPR35-signalling promotes gastrointestinal inflammatory metaplasia and cancer disease biology. In recent years, immunotherapy agents, such as checkpoint inhibitors, have led to dramatic survival benefits in some cancer patients. However, the majority of patients still do not respond adequate...