Company profile
UK company 13767202, incorporated on 26 November 2021.
Apini Therapeutics Limited is a UK company with status active founded in 2021 based in East of England.
Company number 13767202
Updated 07 Jul 2026 09:49
Reference milestones and recent Companies House filing stream events.
Company registered at Companies House
Apini Therapeutics develops small molecule compounds which aim to treat chronic inflammatory diseases.
Development of eNAMPT modulators as a therapeutic approach to the treatment of Tiple Negative Breast Cancer. The data from this study partly underpins Apini Therapeutics, a spin out formed in late 2021 to develop the Manchester eNAMPT modulators, which is currently seeking to raise £3.4M seed funding.
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This work is ongoing, however initial data on the effects of eNAMPT on the proliferation and migration of cancer cell lines in vitro shows a more limited effect than seen the literature. As a result we are no longer investigating the direct anti-tumour effects, however we do observe significant release of eNAMPT in cell cultures so are following up on the impact of this on innate immune cells to understand and validate role of NAMPT and our eNAMPT modulators in this setting. The spin out company will provide economic benefits through likely international commercialisation of a UK-discovered and developed drug with a potential market value of >$1Bn pa.
