Randox Laboratories Limited

**The Northern Ireland Precision Biomarkers and Therapeutics Consortium (NIPBT)** is a partnership of Life and Health Science (LHS) companies and Academia, aligned to the strategies of both the Departments of Health and Economy of the NI devolved government to enhance health and wealth creation for NI citizens. Currently, NI has a significant presence in ...

"Acute Respiratory Distress Syndrome (ARDS) is a life threatening condition in critically ill patients, caused by infection or injury. Infection and injury induce inflammation in the lungs, causing the lungs to fill up with fluid thus preventing the normal movement of oxygen from the lungs to the blood, for distribution to the rest of the body. ARDS often...

he engineering capability of products for life science has advanced in recent years. Global producers of life science tools, analysers etc. has increased also, putting impetus on manufacturing. Manufacturing automation is now a standard for maximising productivity and yield of production and to minimise cost to improve competitiveness. As such this projec...

Chronic kidney disease (CKD) affects 10-15% of the adult population. Progression to end stage kidney disease (ESKD) is a leading cause of morbidity and mortality worldwide with 2.6 million people receiving renal replacement therapy (dialysis or transplantation) in 2010. Numbers continue to increase markedly as a result of the global epidemics of type 2 di...

Abstract: In 2012, 5242 people in the UK lost their life to bladder cancer. The most common symptom of bladder cancer is blood in the urine (haematuria), which is usually painless. Haematuria can be frank (macroscopic), visible to the patient, or invisible (microscopic), which is normally detected during a routine urine dipstick test. Haematuria in its vi...

For the 2,900 patients per year in the UK diagnosed with Acute Myeloid Leukemia (AML), aggressive cytarabine based chemotherapy is given at diagnosis, yet, up to 40% of patients do not respond to this treatment. The majority of AML patients are >60 years old and, with the rise in the elderly population, increased prevalence of the disease is predicted. Cu...

To develop a rapid near-patient test for the detection of bacterial infection in the sputum of patients with chronic infective lung disease.

Sepsis kills 30 000 people in the UK and costs the NHS £400 million per year. It is little known outside the medical profession but is the third most common cause of death in hospitalised patients outside of heart disease and cancer. It happens when an infection in the bloodstream tips the immune system out of balance and this system starts to attack the ...

Diagnosis of SIRS & sepsis and identification of patients likely to progress to severe sepsis or septic shock is challenging due to a lack of definitive diagnostic tests. This project aims to identify biomarker panels for diagnosis and prognosis of SIRS, sepsis and likely progression to severe sepsis from patient host biomarkers identified in previously p...

Awaiting Public Summary

The Automated Multiplex Detection of Veterinary Drug Residues in Food Products

To develop a molecular diagnostic test for detection of multiple aerobic and anaerobic bacteria and viruses causing lung infection in people with cystic fibrosis.