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100,000
2013-09-01 to 2015-06-30
GRD Proof of Concept
The world population continues to expand at an alarming rate bringing with it poverty & hardship. Female sterilisation is the most widely used practical method of family planning worldwide. However an ideal method does not exist. J Guillebaud – Contraception your questions answered 4th Edition 2004. Approximately 180 women of reproductive age around the world are protected from unintended pregnancy by sterilisation (Ross et al 1985). Female sterilisation by laparoscopic occlusion of the fallopian tubes is a widely used method for family planning because of its proven safety & effectiveness (Ms Swain H & Brodie MF 2006). However laparoscopic procedures which involve the use of abdominal instrumentation & require general anaesthetic are not without major complications (Jansen F W et al 1997 & Esobedo et al 1980) @ 1 per 1,000 procedures in USA although they rarely cause death. However low morbidity & mortality rates have to be revised in light of the enormous numbers of procedures @ 1 million & in USA (Tuland T 1977) & 14 million globally per annum. The current hysteroscopic method/product is expensive @ £450 per tube, is not reversible & cannot be used for the treatment of Hydrosalpinx to improve the conception rate. OI Medical Ltd is developing the international intellectual property for a low cost novel hysteroscopic method which has a high chance of being reversible & is looking to prove the concept & use it in small clinical tests. The economic & social benefits are considerable with a market worth £7B p.a. & with unwanted pregnancy, children have a higher incidence of psychiatric disorders, educational deficiencies, delinquency, criminal behaviour & alcoholism (Ney 1978 & 1979).