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Company profile

Leaf Expression Systems Limited

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Cutting-edge plant-based expression & production of proteins. Research & product development. Versatile SupraVec technology & knowledge of plant biotechnology.

CRN
09351695
Founded
2014
Age
11

Overview

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Legal name
LEAF EXPRESSION SYSTEMS LIMITED
Region
East of England
Registered address
C/O LARKING GOWEN LLP, 1ST FLOOR, PROSPECT HOUSE
ROUEN ROAD
NORWICH
NORFOLK
NR1 1RE
Insolvency history
No

Corporate ownership

Updated 06 Jun 2026 16:52

2 levels 1 ultimate controller Controls 1
1
Company Active LTD
Leaf Expression Systems Limited
CRN 09351695
2
Direct controller Active PRIVATE-LIMITED-GUARANT-NSC
JOHN Innes Centre
CRN 00511709
3
Ultimate controller Active PRIVATE-LIMITED-GUARANT-NSC-LIMITED-EXEMPTION
JOHN Innes Foundation
CRN 05574485

Company events

Reference milestones and recent Companies House filing stream events.

9 events
31 Dec
2024

Accounts due

Accounts Due

Next accounts due date

25 Dec
2024

Confirmation statement due

Confirmation Due

Next confirmation statement due date

12 Aug
2024

Liquidation Voluntary Statement Of Affairs

Insolvency

LIQ02 | Transaction MzQzMTM0ODAzNGFkaXF6a2N4 | Paper/PDF filed

Published 13 Aug 2024 07:53

08 Aug
2024

Liquidation Voluntary Appointment Of Liquidator

Insolvency

600 | Transaction MzQzMTIwMDQxMGFkaXF6a2N4 | Paper/PDF filed

Published 09 Aug 2024 10:00

08 Aug
2024

Resolution

Resolution

RESOLUTIONS | Transaction WUQ4Vks2TTBhZGlxemtjeA | Paper/PDF filed

Published 09 Aug 2024 09:59

08 Aug
2024

Change Registered Office Address Company With Date Old Address New Address

Address

AD01 | Transaction MzQzMTIwMDQ0NWFkaXF6a2N4 | Paper/PDF filed

Published 09 Aug 2024 09:59

11 Dec
2023

Confirmation statement filed

Confirmation

Last confirmation statement made up date

31 Mar
2023

Accounts filed

Accounts

Last accounts made up date

11 Dec
2014

Incorporated

Inception

Company registered at Companies House

Spinout profile

5 entries

Company description

Leaf Systems® International Limited is a new contract development business specialising in the expression and production of proteins, metabolites and complex natural products for research and bio-medical applications using a proprietary, transient expression technology. Leaf Systems uses the proprietary Hypertrans® expression technologies developed by Prof.George Lomonossoff at the John Innes Centre, UK. The Hypertrans system allows for the simultaneous production of multiple gene products in a controlled and coordinated manner within the tissues of plants. Using gene synthesis and modular vectors, new products can be developed, validated, scaled and produced very quickly. Leaf Systems is employing state of the art containment facilities to produce and engineer its feedstock plants and has industry standard downstream processing capabilities to ensure production quality and bio-security. Leaf Systems works with companies as a contract development organisation to develop and scale the production of their products or intermediates. We also work alongside academic scientists to translate their science into scalable processes or to develop new enabling technologies, including as a collaborator on grants. Leaf Systems has SME status and is available to participate in translational research and development consortia, including EU framework programs.

Leaf Expression Systems is a plant biotechnology company that offers contract research and product development services, specializing in plant-based expression and production of proteins for companies in the life sciences, food, agribiotech, and consumer care industries.

Project impact

As it is less than a year old, it is too soon for Leaf Systems to have had an impact yet.

Leaf Systems International
2016
Leaf Expression Systems
2014
Leaf Expression Systems
2014
Leaf Expression Systems
2014
Leaf Expression Systems
2014

Public funding

1 award
First funded
2017
Funded years
2017
Age at first award
2 years

Projects

2017 Small Business Research Initiative Lead participant

Project Title: Development of Virus-Like Particles as vaccines against emerging viral diseases

1 Apr 2017 to 31 Mar 2018

Awarded
£490,375
Total cost £490,375

"Development of Virus-Like Particles as vaccines against emerging viral diseases" Recent decades have seen changes in the mobility of arthropod vectors, driven by global warming. This has resulted in the spread of several diseases from their previously restricted ranges into larger naïve human and animal populations, resulting in severe epidemics. In addi...

Product types

Small Business Research Initiative