Spinout Active LTD

Company profile

Epsilogen Ltd

Home - Epsilogen

Epsilogen Ltd is a UK company with status active founded in 2016.

CRN
10295520
Founded
2016
Age
9

Overview

Browse spinouts
Legal name
EPSILOGEN LTD
Region
Unknown
Registered address
WATERFRONT, ARC WEST LONDON MANBRE ROAD
HAMMERSMITH
LONDON
UNITED KINGDOM
W6 9RH
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

13 events
30 Sep
2026

Accounts due

Accounts Due

Next accounts due date

08 Aug
2026

Confirmation statement due

Confirmation Due

Next confirmation statement due date

25 Jul
2025

Confirmation statement filed

Confirmation

Last confirmation statement made up date

31 Dec
2024

Accounts filed

Accounts

Last accounts made up date

10 Sep
2024

Capital Allotment Shares

Capital

SH01 | Transaction MzQzNDk1NTExN2FkaXF6a2N4

Published 10 Sep 2024 09:25

06 Sep
2024

Capital Allotment Shares

Capital

SH01 | Transaction MzQzNDgwMTc5NmFkaXF6a2N4

Published 06 Sep 2024 17:23

05 Sep
2024

Capital Allotment Shares

Capital

SH01 | Transaction MzQzNDUxMDQwNWFkaXF6a2N4

Published 05 Sep 2024 09:06

04 Sep
2024

Capital Allotment Shares

Capital

SH01 | Transaction MzQzNDQ5NzgxOWFkaXF6a2N4

Published 04 Sep 2024 13:53

12 Aug
2024

Confirmation Statement With Updates

Confirmation-statement

CS01 | Transaction MzQzMTg1MzY0OGFkaXF6a2N4

Published 12 Aug 2024 13:06

09 Aug
2024

Cessation Of A Person With Significant Control

Persons-with-significant-control

PSC07 | Transaction MzQzMTcxMDQxN2FkaXF6a2N4

Published 09 Aug 2024 10:24

09 Aug
2024

Notification Of A Person With Significant Control Statement

Persons-with-significant-control

PSC08 | Transaction MzQzMTcxMDQxOGFkaXF6a2N4

Published 09 Aug 2024 10:24

09 Aug
2024

Cessation Of A Person With Significant Control

Persons-with-significant-control

PSC07 | Transaction MzQzMTcxMDQxNmFkaXF6a2N4

Published 09 Aug 2024 10:24

26 Jul
2016

Incorporated

Inception

Company registered at Companies House

Spinout profile

2 entries

Company description

Epsilogen develops drugs for use in immuno-oncology, specifically antibodies that can target and destroy solid tumours.

Project impact

Epsilogen Ltd. is developing a novel antibody platform technology based on engineering of the epsilon constant region.

Public funding

4 awards
First funded
2018
Funded years
2018, 2019, 2020
Age at first award
1 years

Projects

2020 Study Lead participant

Preclinical validation of a novel cancer immunotherapeutic

1 Oct 2020 to 31 Dec 2022

Awarded
£492,545
Total cost £703,636

Epsilogen (formerly IGEM Therapeutics) is developing a novel HER2-targeted antibody EPS 201, selected on a number of key attributes that sets it apart from marketed competitors. The project seeks to move EPS 201 closer to the clinic through development of product quality assays, _in vivo_ models for GLP toxicology and efficacy, and a manufacturing cell li...

2020 Study Lead participant

Next generation antibody treatments for ovarian cancer

1 May 2020 to 31 Oct 2021

Awarded
£348,520
Total cost £497,885

IGEM Therapeutics Ltd aims to develop new platform technologies for creating therapeutic IgE molecules with enhanced anti-tumour activities. The Fc region of IgE has been engineered to introduce additional functionality with a view to improving anti-tumour responses, in particular for treatment of solid tumours. An immediate output of the project will be ...

2019 Feasibility Studies Lead participant

Discovery of next generation HER2 antibodies for the treatment of cancer

1 Jan 2019 to 30 Nov 2020

Awarded
£523,217
Total cost £747,453

IGEM Therapeutics Ltd aims to develop a novel HER2-targeted antibody that will address a number of unmet clinical needs. It will exploit innovative animal models, novel HER2-binding antibody domains and its innovative IgE platform technology. IgE provides a completely unique anti-cancer mode of action which enables our products to be clearly differentiate...

2018 Collaborative R&D Lead participant

Development of a novel immuno-oncology drug targeting solid tumours

1 Apr 2018 to 30 Jun 2020

Awarded
£1,018,198
Total cost £1,454,568

IGEM-C is an IgE-based antibody targeting a melanoma antigen. The project involves the evaluation of a number of novel variants of the prototype for efficacy, manufacturability and stability. The antigen target for IGEM-C is found in many different solid tumours, and part of the project will be to develop animal models for these indications. The chosen va...

Product types

Collaborative R&D Feasibility Studies Study