Company profile
Epsilogen Ltd
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Epsilogen Ltd is a UK company with status active founded in 2016.
Company events
Reference milestones and recent Companies House filing stream events.
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Accounts filed
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Capital Allotment Shares
CapitalSH01 | Transaction MzQzNDk1NTExN2FkaXF6a2N4
Published 10 Sep 2024 09:25
Capital Allotment Shares
CapitalSH01 | Transaction MzQzNDgwMTc5NmFkaXF6a2N4
Published 06 Sep 2024 17:23
Capital Allotment Shares
CapitalSH01 | Transaction MzQzNDUxMDQwNWFkaXF6a2N4
Published 05 Sep 2024 09:06
Capital Allotment Shares
CapitalSH01 | Transaction MzQzNDQ5NzgxOWFkaXF6a2N4
Published 04 Sep 2024 13:53
Confirmation Statement With Updates
Confirmation-statementCS01 | Transaction MzQzMTg1MzY0OGFkaXF6a2N4
Published 12 Aug 2024 13:06
Cessation Of A Person With Significant Control
Persons-with-significant-controlPSC07 | Transaction MzQzMTcxMDQxN2FkaXF6a2N4
Published 09 Aug 2024 10:24
Notification Of A Person With Significant Control Statement
Persons-with-significant-controlPSC08 | Transaction MzQzMTcxMDQxOGFkaXF6a2N4
Published 09 Aug 2024 10:24
Cessation Of A Person With Significant Control
Persons-with-significant-controlPSC07 | Transaction MzQzMTcxMDQxNmFkaXF6a2N4
Published 09 Aug 2024 10:24
Incorporated
InceptionCompany registered at Companies House
Spinout profile
Company description
Epsilogen develops drugs for use in immuno-oncology, specifically antibodies that can target and destroy solid tumours.
Project impact
Epsilogen Ltd. is developing a novel antibody platform technology based on engineering of the epsilon constant region.
Public funding
Projects
Preclinical validation of a novel cancer immunotherapeutic
1 Oct 2020 to 31 Dec 2022
Epsilogen (formerly IGEM Therapeutics) is developing a novel HER2-targeted antibody EPS 201, selected on a number of key attributes that sets it apart from marketed competitors. The project seeks to move EPS 201 closer to the clinic through development of product quality assays, _in vivo_ models for GLP toxicology and efficacy, and a manufacturing cell li...
Next generation antibody treatments for ovarian cancer
1 May 2020 to 31 Oct 2021
IGEM Therapeutics Ltd aims to develop new platform technologies for creating therapeutic IgE molecules with enhanced anti-tumour activities. The Fc region of IgE has been engineered to introduce additional functionality with a view to improving anti-tumour responses, in particular for treatment of solid tumours. An immediate output of the project will be ...
Discovery of next generation HER2 antibodies for the treatment of cancer
1 Jan 2019 to 30 Nov 2020
IGEM Therapeutics Ltd aims to develop a novel HER2-targeted antibody that will address a number of unmet clinical needs. It will exploit innovative animal models, novel HER2-binding antibody domains and its innovative IgE platform technology. IgE provides a completely unique anti-cancer mode of action which enables our products to be clearly differentiate...
Development of a novel immuno-oncology drug targeting solid tumours
1 Apr 2018 to 30 Jun 2020
IGEM-C is an IgE-based antibody targeting a melanoma antigen. The project involves the evaluation of a number of novel variants of the prototype for efficacy, manufacturability and stability. The antigen target for IGEM-C is found in many different solid tumours, and part of the project will be to develop animal models for these indications. The chosen va...