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Browse spinoutsCompany number 10295520
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UK company 10295520, incorporated on 26 July 2016.
Home - Epsilogen
Epsilogen Ltd is a UK company with status Active founded in 2016.
Company number 10295520
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Epsilogen develops drugs for use in immuno-oncology, specifically antibodies that can target and destroy solid tumours.
Epsilogen Ltd. is developing a novel antibody platform technology based on engineering of the epsilon constant region.
1 Oct 2020 to 31 Dec 2022
Epsilogen (formerly IGEM Therapeutics) is developing a novel HER2-targeted antibody EPS 201, selected on a number of key attributes that sets it apart from marketed competitors. The project seeks to move EPS 201 closer to the clinic through development of product quality assays, _in vivo_ models for GLP toxicology and efficacy, and a manufacturing cell li...
1 May 2020 to 31 Oct 2021
IGEM Therapeutics Ltd aims to develop new platform technologies for creating therapeutic IgE molecules with enhanced anti-tumour activities. The Fc region of IgE has been engineered to introduce additional functionality with a view to improving anti-tumour responses, in particular for treatment of solid tumours. An immediate output of the project will be ...
1 Jan 2019 to 30 Nov 2020
IGEM Therapeutics Ltd aims to develop a novel HER2-targeted antibody that will address a number of unmet clinical needs. It will exploit innovative animal models, novel HER2-binding antibody domains and its innovative IgE platform technology. IgE provides a completely unique anti-cancer mode of action which enables our products to be clearly differentiate...
1 Apr 2018 to 30 Jun 2020
IGEM-C is an IgE-based antibody targeting a melanoma antigen. The project involves the evaluation of a number of novel variants of the prototype for efficacy, manufacturability and stability. The antigen target for IGEM-C is found in many different solid tumours, and part of the project will be to develop animal models for these indications. The chosen va...