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Company profile

Cytoseek Limited

CytoSeek

Enabling the next generation of cell therapies for solid tumours through Artificial Membrane-Binding Proteins. CytoSeek is a preclinical biotech company based in Bristol, UK.

CRN
11076788
Founded
2017
Age
8

Overview

Browse spinouts
Legal name
HONE BIO LIMITED
Region
South West England
Registered address
SCIENCE CREATES OLD MARKET
MIDLAND ROAD
BRISTOL
ENGLAND
BS2 0JZ
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

5 events
05 Dec
2026

Confirmation statement due

Confirmation Due

Next confirmation statement due date

31 Jul
2026

Accounts due

Accounts Due

Next accounts due date

21 Nov
2025

Confirmation statement filed

Confirmation

Last confirmation statement made up date

31 Jul
2024

Accounts filed

Accounts

Last accounts made up date

22 Nov
2017

Incorporated

Inception

Company registered at Companies House

Spinout profile

5 entries

Company description

CytoSeek develops cell membrane augmentation technology, with applications in cell therapies for various disorders.

Next generation cell therapies CytoSeek is developing its Artificial Membrane Binding Protein (AMBP) technology to enhance cell therapies for use in tumour therapies. AMBPs, which bind to virtually all cell types, have a modular design that allows rapid prototyping to deliver new functionalities. Currently, we are developing AMBPs that can provide homing, immunomodulation, and/or hypoxia resistance functionality.

Hone Bio develops cell membrane augmentation technology, with applications in cell therapies for various disorders.

Project impact

None yet

Not yet evaluated.

Public funding

4 awards
First funded
2018
Funded years
2018, 2019, 2020, 2024
Age at first award
0 years

Projects

2024 Collaborative R&D Lead participant

Cell-Specific Targeting of Advanced Therapeutics via Next Generation Artificial Membrane-Binding Proteins

1 May 2024 to 31 Oct 2025

Awarded
£548,072
Total cost £782,960

This project, inspired by the success of lipid nanoparticle (LNP) based COVID-19 vaccines that reached \>1B people worldwide, aims to harness CytoSeek's state-of-the-art Artificial Membrane-Binding Protein (AMBP) technology for the precise targeting of LNPs to specific cell populations. This innovative approach holds potential for delivering advanced canc...

2020 Feasibility Studies Lead participant

CytoSeek continuity grant

1 Jun 2020 to 30 Nov 2020

Awarded
£177,958
Total cost £177,958

no public description

2019 Collaborative R&D Lead participant

Re-engineering T-cell membranes for efficacy against solid tumours

1 Oct 2019 to 30 Sep 2022

Awarded
£306,943
Total cost £613,886

In 2018, more than 9.5 million people worldwide died from cancer, with more than 18 million new cancer incidences reported. A new approach using human immune cells to attack tumours is showing promise in the clinic. Within this exciting new field, CAR-T therapy has been shown to be effective against blood-based cancers, such as acute lymphoblastic leukaem...

2018 Feasibility Studies Lead participant

The development of artificial cell membrane binding proteins

1 Jan 2018 to 30 Sep 2019

Awarded
£93,925
Total cost £137,795

During a heart attack, muscles in the heart suffer damage because of the loss of oxygen. Unfortunately, it is very difficult for the body to repair this damage, which weakens the heart and increases the chance of subsequent heart failure. An exciting new approach to repair this damage involves injecting stem cells into the surrounding areas to help repair...

Product types

Collaborative R&D Feasibility Studies