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Company profile

LRG1 Ltd

Senya Therapeutics

Harnessing LRG1 for long-term health

CRN
11815299
Founded
2019
Age
7

Overview

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Legal name
LRG1 LTD
Region
Unknown
Registered address
90 TOTTENHAM COURT ROAD
LONDON
ENGLAND
W1T 4TJ
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

7 events
31 May
2027

Accounts due

Accounts Due

Next accounts due date

07 Feb
2027

Confirmation statement due

Confirmation Due

Next confirmation statement due date

24 Jan
2026

Confirmation statement filed

Confirmation

Last confirmation statement made up date

31 Aug
2025

Accounts filed

Accounts

Last accounts made up date

22 Sep
2024

Accounts With Accounts Type Micro Entity

Accounts Analysed

AA | Transaction MzQzNjc3OTgwN2FkaXF6a2N4

Published 22 Sep 2024 11:53

07 Aug
2024

Resolution

Resolution

RESOLUTIONS | Transaction WUQ4TlFIVFRhZGlxemtjeA | Paper/PDF filed

Published 08 Aug 2024 08:18

08 Feb
2019

Incorporated

Inception

Company registered at Companies House

Spinout profile

1 entry

Company description

The company has been set up to advance the development of the LRG1 blocking antibody Magacizumab, and also its Fab fragment (that we term MagaFab) specifically for use in ocular indications. The first objectives of the company are to establish that MagaFab is tolerated in the eye and is therefore suitable for onward development towards early stage clinical trials. The company operates under the name PanAngium Therapeutics, and as of early 2021 has a CEO who is leading the search for investment.

Project impact

The company was formed at the start of 2019, so no notable impacts just yet.

LRG1 LTD
2019

Public funding

1 award
First funded
2024
Funded years
2024
Age at first award
5 years

Projects

2024 Collaborative R&D Lead participant

Indication selection, patient stratification, and IND preparation for STX-002: the first-in-class LRG1 inhibitor for treatment of chronic kidney disease and immunotherapy-resistant tumours.

1 May 2024 to 30 Apr 2025

Awarded
£679,484
Total cost £970,692

LRG1 is a secreted glycoprotein that plays a key role in a range of highly prevalent chronic diseases by promoting vascular dysfunction, fibrosis and uncontrolled cell proliferation. Mounting evidence shows its involvement in diseases such as chronic kidney disease (CKD) which affects over 800 million people globally with significant morbidity and mortali...

Product types

Collaborative R&D