Spinout Active LTD

Company profile

LRG1 Ltd

UK company 11815299, incorporated on 8 February 2019.

Senya Therapeutics

Harnessing LRG1 for long-term health

Company number
11815299
Incorporated
8 Feb 2019
Companies House status
Active

Company identity

Browse spinouts
Founded / incorporated
8 February 2019

Company number 11815299

Verify at Companies House
Legal name
LRG1 LTD
Company type
Private Limited Company
Region
Unknown
Registered address
90 TOTTENHAM COURT ROAD
LONDON
ENGLAND
W1T 4TJ
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

6 events
31 Mar
2027

Accounts due

Accounts Due

Next accounts due date

07 Feb
2027

Confirmation statement due

Confirmation Due

Next confirmation statement due date

30 Jul
2026

Change Account Reference Date Company Previous Shortened

Accounts Analysed

AA01 | Transaction MzUzNjA3NDQ3MWFkaXF6a2N4

Published 30 Jul 2026 16:39

24 Jan
2026

Confirmation statement filed

Confirmation

Last confirmation statement made up date

31 Aug
2025

Accounts filed

Accounts

Last accounts made up date

08 Feb
2019

Incorporated

Inception

Company registered at Companies House

Spinout profile

1 entry

Company description

The company has been set up to advance the development of the LRG1 blocking antibody Magacizumab, and also its Fab fragment (that we term MagaFab) specifically for use in ocular indications. The first objectives of the company are to establish that MagaFab is tolerated in the eye and is therefore suitable for onward development towards early stage clinical trials. The company operates under the name PanAngium Therapeutics, and as of early 2021 has a CEO who is leading the search for investment.

Project impact

The company was formed at the start of 2019, so no notable impacts just yet.

LRG1 LTD
2019

Public funding

1 award
First funded
2024
Funded years
2024
Age at first award
5 years

Projects

2024 Collaborative R&D Lead participant

Indication selection, patient stratification, and IND preparation for STX-002: the first-in-class LRG1 inhibitor for treatment of chronic kidney disease and immunotherapy-resistant tumours.

1 May 2024 to 30 Apr 2025

Awarded
£679,484
Total cost £970,692

LRG1 is a secreted glycoprotein that plays a key role in a range of highly prevalent chronic diseases by promoting vascular dysfunction, fibrosis and uncontrolled cell proliferation. Mounting evidence shows its involvement in diseases such as chronic kidney disease (CKD) which affects over 800 million people globally with significant morbidity and mortali...

Product types

Collaborative R&D