Public Funding for Serg Technologies Limited

**SERG ONE DBS - an intelligent mechanomyography sensor platform for precise deep brain stimulation parametrisation to treat Parkinson's Disease** SERG Technologies (Imperial College spin-out), in partnership with St George's University Hospitals NHS Foundation Trust, propose a 15-month industrial research programme focused on developing and evidencing the technical capabilities of our current offering, SERG-one, a patented TRL4 telemedicine, symptomatic assessment device, to become the clinical assessment arm of a novel closed-loop treatment solution for motor symptoms of Parkinson's.

**PD-CL-REHAB - Closed-loop rehabilitation for Parkinson's Disease and wider neurological disorders** An 18-month industrial research project in which SERG Technologies Ltd, in partnership with chartered neurological physiotherapists from the LV Rehabilitation Centre and the Neuromuscular Rehabilitation Technology Network at Imperial College London, will develop the first closed-loop, at-home, rehabilitation platform for Parkinson's Disease and wider neurological disorders - PD-Rehab.

NuRO.sense - An intelligent wearable to assess and monitor the motor symptoms of neurodegeneration

SERG Technologies Ltd has developed a new, revolutionary, wearable sensor suite for the investigation and monitoring of muscular rigidity and underlying neural signals in Parkinson's Disease (PD). Our patented technology has the potential to be employed in telemedicine for automated accurate assessment of PD symptom severity enabling vulnerable people that cannot visit their neurologist due to the COVID-19 pandemic to be independent and maintain their quality of living. Our system is reliable, user-and-doctor-friendly, and unique as it is the only device capable of an assessment of all cardinal PD symptoms within the current framework of current NHS neurological tests. In addition, it can be utilised as a future means of continuous closed-loop deep brain stimulation (DBS) for patients with PD, providing a foundation for a range of ground-breaking, new, neurostimulation treatments.