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Company profile

Senisca Ltd

Reverse Cell Ageing - Senisca

Senisca Ltd is a UK company with status active founded in 2020 based in South West England.

CRN
12948837
Founded
2020
Age
5

Overview

Browse spinouts
Legal name
SENISCA LTD
Region
South West England
Registered address
INNOVATION CENTRE UNIVERSITY OF EXETER
RENNES DRIVE
EXETER
DEVON
ENGLAND
EX4 4RN
Insolvency history
No

Corporate ownership

Updated 06 Jun 2026 16:52

Senisca Ltd
No active corporate controller recorded.

Latest accounts

Financial period: 1 Jan 2024 to 31 Dec 2024

FULLACCOUNTS
Turnover
Unknown
Profit / Loss
-£1,965,083
Employees
18

Company events

Reference milestones and recent Companies House filing stream events.

8 events
30 Sep
2027

Accounts due

Accounts Due

Next accounts due date

26 Oct
2026

Confirmation statement due

Confirmation Due

Next confirmation statement due date

31 Dec
2025

Accounts filed

Accounts

Last accounts made up date

12 Oct
2025

Confirmation statement filed

Confirmation

Last confirmation statement made up date

15 Oct
2024

Confirmation Statement With Updates

Confirmation-statement

CS01 | Transaction MzQzOTU0MTIzN2FkaXF6a2N4

Published 15 Oct 2024 10:23

27 Sep
2024

Appoint Person Director Company With Name Date

Officers

AP01 | Transaction MzQzNzE2OTMxMWFkaXF6a2N4

Published 27 Sep 2024 12:29

12 Aug
2024

Accounts With Accounts Type Total Exemption Full

Accounts Analysed

AA | Transaction MzQzMTg2NTIyMGFkaXF6a2N4

Published 12 Aug 2024 14:53

13 Oct
2020

Incorporated

Inception

Company registered at Companies House

Spinout profile

3 entries

Company description

Senisca develops technology that aims to reverse cellular senescence.

SENISCA Ltd. Spun out from University of Exeter in Oct 20. Currently at 10x FTE positions in UK with a further 0.5x FTE position embedded in labs at Murdoch University.

Project impact

SENISCA Ltd. Spun out from University of Exeter in Oct 20. Currently at 10x FTE positions in UK with a further 0.5x FTE position embedded in labs at Murdoch University.

Senisca
2020
SENISCA LTD
2020

Public funding

4 awards
First funded
2021
Funded years
2021, 2022, 2023
Age at first award
0 years

Projects

2023 Collaborative R&D Lead participant

Oligonucleotide therapeutics to transform IPF treatment

1 May 2023 to 31 Oct 2025

Awarded
£571,350
Total cost £816,215

Here we propose a highly innovative RNA medicine project that will leverage the previous work carried out by SENISCA on the identification of a new and druggable set of target genes to enable significant senescence reversal effect in primary human cell lines. This project is a step forward towards the most innovative and fruitful avenue for novel therapeu...

2022 Collaborative R&D Lead participant

Developing a molecular clock for evaluation of senotherapeutics

1 Apr 2022 to 31 Mar 2023

Awarded
£184,252
Total cost £263,217

At SENISCA we have discovered a new way by which cells age; loss of alternative splicing, a form of fine-tuning of gene expression. We can restore this process to 'turn back the ageing clock' in old (senescent) human cells. This presents a possible solution to many of the healthcare challenges faced by our ageing society, offering restorative, as well as ...

2022 Collaborative R&D Lead participant

Developing SENISCA's global network to meet future needs: grant applications, oligonucleotide synthesis, and pharmaceutical partners

1 Jan 2022 to 31 Mar 2022

Awarded
£19,869
Total cost £28,384

SENISCA is a biotech spinout company from the University of Exeter, founded in 2020 and dedicated to the development of new approaches to reverse cellular senescence (senotherapeutics). Our founders are world leaders in molecular and cellular biology and have patent-protected an innovation for the reversal of cell aging. This innovation works by restoring...

2021 Study Lead participant

Developing treatments to turn back the 'cellular clock'

1 Mar 2021 to 31 May 2022

Awarded
£240,612
Total cost £240,612

Ageing is a universal phenomenon and the primary risk factor for most common, chronic human diseases. Our company, SENISCA, is a spin-out from the University of Exeter, initially focussing on developing molecules suitable for treatment of skin ageing, followed by a wider vision to deliver innovative, effective pharmaceutical treatments for age-related dis...

Product types

Collaborative R&D Study