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Public Funding for Solena Materials Limited

Registration Number 13526395

Characterisation of new-to-world synthetic proteins for high-performance, sustainable textiles

9,972
2024-11-01 to 2025-01-31
Collaborative R&D
Our project aims to revolutionise the sustainable materials market by characterising the unique properties of Solena's innovative materials. This project aims to demonstrate that our fibres have the potential to transform various industries, including fashion, healthcare, and consumer goods, by providing high performance while also reducing the environmental impact. The proteins which form the basis of our sustainable fibres are designed in-house and are thus completely new-to-world, therefore understanding the composition and properties of the fibres is crucial to demonstrating their competitiveness. This challenge is further compounded by the need for a high throughput -- our deep learning models design many candidate proteins to be compared. Therefore, our samples are incompatible with most conventional materials characterisation techniques. Measurement of the key material properties would enable us to rapidly choose the most optimal proteins and fabrication conditions for scaling up production. By partnering with the National Physical Laboratory (NPL), we would be able to demonstrate how our fibres surpass natural and synthetic alternatives on the market, and obtain a much larger dataset of the material properties for our different protein fibres. We would then use these measurements as training data for our models, which would enable us to not only optimise the protein design much more quickly and accurately, but to rapidly explore new protein spaces. We could then start to bring our products to market. The expected outputs of this project include the first measurements of a variety of material properties of our fibres, knowhow on the effect of fibre production parameters on these properties, and a final report. These outputs will help Solena develop improved protein fibres and thus cater to the increasing demand for high-performance and environmentally friendly materials. This project also represents a significant leap forward in the development of sustainable materials, with the potential to disrupt various industries by offering high-performance, bio-based alternatives to petrochemical-derived synthetic materials. The successful execution of this project, in partnership with NPL, will not only position us as a leader in the sustainable materials market by enabling us to attract new customers who are seeking specific material properties, but also contribute to meeting global climate goals and fostering a greener, more sustainable future.

The Manufacturing of De Novo Designed Protein Fibres

171,335
2024-02-01 to 2025-01-31
Collaborative R&D
Our groundbreaking project is set to revolutionize the sustainable materials market by developing innovative and cost-effective methods for producing a new generation of protein-based materials. These materials have the potential to transform various industries, including fashion, healthcare, and consumer goods, by providing high-performance, environmentally friendly alternatives to conventional materials. Using cutting-edge technologies like AI-driven protein design, laboratory automation, and our proprietary screening platform, our unique approach accelerates the development of custom protein-based materials. These materials aim to address the challenge of producing high-performance, sustainable biomaterials that can be scaled up to industrial processes. In partnership with the Centre for Process Innovation (CPI), we will develop novel bioprocesses to manufacture our materials in a cost-effective manner. Central to this project is the use of an industrially relevant expression host known for its robustness and high protein yields. Our technology designs completely new protein sequences from scratch, avoiding the issues associated with using natural protein sequences. This innovative approach allows us to develop high-performance, sustainable bio-based alternatives to petrochemical-derived synthetic materials. The expected outputs of this project include innovative bioprocesses, new recombinant protein expression strains, and a final report. These outputs will help meet the growing demand for high-performance and environmentally friendly materials. This project represents a significant leap forward in the development of sustainable materials, with the potential to disrupt various industries by offering high-performance, bio-based alternatives to petrochemical-derived synthetic materials. The successful execution of this project, in partnership with CPI, will not only position us as a leader in the sustainable materials market but also contribute to meeting global climate goals and fostering a greener, more sustainable future.

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