Public Funding for Bainbridge Bio Ltd

Chemotherapy, a cornerstone of cancer treatment, hinges on maintaining precise drug levels in the patient's body. However, the current generalised dosing protocol requires frequent blood draws, is costly, time-consuming, and uncomfortable for patients. To address these issues, we propose an innovative project to develop a finger-prick sensor for instant drug and biomarker monitoring. This technology leverages a novel approach to electrochemical, aptamer-based sensing, offering a solution that could transform patient monitoring in oncology. Our primary objective is to design, develop, and validate a sensor for commonly monitored chemotherapies, inspired by recent technologies from the University of Cambridge and 2bind GmbH. Through the ability to select and implement new aptamers, we intend to establish a comprehensive sensor development pipeline. This system will allow commercialisation partners to quickly implement custom sensors for a variety of small molecule targets. Our project aims to deliver a cutting-edge solution that could revolutionise diagnostic monitoring, starting in oncology and setting a new standard for personalised and patient-centred cancer treatment in the UK and worldwide.