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Proaxsis Ltd

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ProAxsis develops and supplies diagnostic assays focusing on biomarkers that aid clinical intervention which leads to improved patient outcomes.

CRN
NI619901
Founded
2013
Age
12

Overview

Browse spinouts
Legal name
PROAXSIS LTD
Region
Northern Ireland
Registered address
BUILDING 75, RANDOX SCIENCE PARK
30 RANDALSTOWN ROAD
ANTRIM
NORTHERN IRELAND
BT41 4FL
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

7 events
30 Sep
2026

Accounts due

Accounts Due

Next accounts due date

26 Aug
2026

Confirmation statement due

Confirmation Due

Next confirmation statement due date

12 Aug
2025

Confirmation statement filed

Confirmation

Last confirmation statement made up date

31 Dec
2024

Accounts filed

Accounts

Last accounts made up date

26 Nov
2024

Gazette Notice Compulsory

Gazette

GAZ1 | Transaction MzQ0NDIxNTk2MGFkaXF6a2N4 | Paper/PDF filed

Published 23 Nov 2024 11:04

19 Aug
2024

Confirmation Statement With Updates

Confirmation-statement

CS01 | Transaction MzQzMjYxMDEyM2FkaXF6a2N4

Published 19 Aug 2024 10:55

16 Aug
2013

Incorporated

Inception

Company registered at Companies House

Spinout profile

3 entries

Company description

The work carried out in Dr Martin's CiC project in 2012, also attracted the early attention of AIM listed NetScientific plc, a healthcare medical technology company that commercialises research and technologies originating from leading universities. Working in partnership with NetScientific accelerated the formation of a new University spin-out venture called ProAxsis Ltd. The company has secured a range of investors including venture funding alongside Netscientific and others.

ProAxsis is an in vitro diagnostics company in Northern Ireland that focuses on respiratory diagnostic assays to aid clinical intervention and improve patient outcomes.

ProAxsis has developed a range of tools to detect and monitor chronic diseases including cystic fibrosis and chronic obstructive pulmonary disease.

Project impact

ProAxsis was named as one of Northern Ireland's most promising technology companies, winning the annual NISP Connect 25K awards in 2013 and recently secured funding from the first round of EU Horizon 2020 funding for small businesses. By 2018, the key technology licenced into the company from the original funded project had achieved CE mark status. In addition, the company's ProteaseTag® Active NE Immunoassay, and NEATstik®, the first test to enable measurement of active neutrophil elastase at point-of-care, have been selected for inclusion in a major upcoming clinical trial. The BRIDGE study is a 3-year collaborative study, funded by the European Respiratory Society (ERS), in which 1000 patients with bronchiectasis across Europe will be recruited and will have multiple assessments including microbiome, proteomics, detailed phenotyping and imaging. The study will explore novel biomarkers and demonstrate what they can add to clinical practice.

ProAxsis Ltd
2014
ProAxsis
2013
ProAxsis
2013

Public funding

8 awards
First funded
2017
Funded years
2017, 2020, 2021, 2022, 2024
Age at first award
3 years

Projects

2024 Collaborative R&D

Future Medicines Institute Application

1 Nov 2024 to 31 Oct 2029

Awarded
£845,649
Total cost £1,208,243

**The Northern Ireland Precision Biomarkers and Therapeutics Consortium (NIPBT)** is a partnership of Life and Health Science (LHS) companies and Academia, aligned to the strategies of both the Departments of Health and Economy of the NI devolved government to enhance health and wealth creation for NI citizens. Currently, NI has a significant presence in ...

2024 Collaborative R&D Lead participant

Enhanced stratification of COPD patients via integration of a digitally enabled biomarker Point-of-Care test within a Remote Patient Monitoring tool

1 Apr 2024 to 31 Dec 2025

Awarded
£333,521
Total cost £476,459

The enzyme Neutrophil Elastase (NE) is associated with the severity of several respiratory diseases, including Chronic Obstructive Pulmonary Disease (COPD), where repeated cycles of infection and inflammation leads to active NE release from immune cells, causing lung damage. Active NE is predictive of lung function loss and is the most informative biomark...

2022 EU-Funded Lead participant

Rapid point-of-care test for osteoporotic fracture risk prediction in Type-2 Diabetes patients

1 Aug 2022 to 31 Jan 2025

Awarded
£289,389
Total cost £482,315
2021 Responsive Strategy and Planning Lead participant

Creation of a novel monitoring tool to predict abnormal coagulation in COVID-19.

1 Oct 2021 to 31 Dec 2022

Awarded
£144,685
Total cost £321,522

The formation of blood clots has been identified as a potential risk factor for a very small proportion of individuals receiving certain types of COVID-19 vaccine. A larger proportion of people who have tested positive for COVID-19 (the infectious disease caused by the coronavirus) have also experienced inappropriate blood clotting, which has resulted in ...

2020 Collaborative R&D Lead participant

COVID-19: Novel protease biomarkers to identify high-risk patients

1 Sep 2020 to 30 Nov 2021

Awarded
£271,448
Total cost £387,783

ProAxsis is a Northern Ireland-based company which specialises in the measurement of a group of enzymes called proteases. Current tests being developed to support the fight against COVID-19 (the infectious disease caused by coronavirus) are focused on identifying patients who currently have, or have previously had, the virus. Whilst this is clearly useful...

2020 Feasibility Studies Lead participant

A novel multiplex cytokine respiratory panel to change the dynamics of COVID-19 testing

1 Jun 2020 to 28 Feb 2021

Awarded
£74,948
Total cost £74,948

There are a number of markers of inflammation which have been associated with various diseases. One group of such markers is the cytokines which are small proteins released by different cells in the body. These cytokines work as messengers and help co-ordinate the body's fight against infection and inflammation. Cytokines are often measured in the blood o...

2017 Feasibility Studies Lead participant

Development of technology to support the advance of new protease therapeutics

1 Jul 2017 to 31 Mar 2018

Awarded
£57,390
Total cost £95,650

Neutrophil Elastase (NE) activity is associated with the severity of respiratory diseases including Cystic Fibrosis (CF) Chronic Obstructive Pulmonary Disease (COPD) and bronchiectasis. In these diseases repeated cycles of infection and inflammation result in the release of NE which causes lung damage. NE is predictive of loss of lung function and is the ...

2017 Feasibility Studies Lead participant

Feasibility Study for an activity-based Immunoassay for the detection of pancreatic elastase

1 Feb 2017 to 31 Jan 2018

Awarded
£79,967
Total cost £133,279

Pancreatic Insufficiency (PI) is a condition that occurs in a range of diseases including chronic pancreatitis, pancreatic cancer, diabetes, cystic fibrosis and inflammatory bowel disorders. Often, diagnosis is delayed as symptoms don't appear until almost all of the pancreatic function is lost. Pancreatic Elastase (PE), one of the enzymes normally releas...

Product types

Collaborative R&D EU-Funded Feasibility Studies Responsive Strategy and Planning