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Company profile

Sphere Fluidics Limited

Sphere Fluidics Limited

Automated high-throughput single cell analysis platforms based on microfluidic picodroplet technology

CRN
07167872
Founded
2010
Age
16

Overview

Browse spinouts
Legal name
SPHERE BIO LIMITED
Region
London
Registered address
30 OLD BAILEY
LONDON
EC4M 7AU
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

11 events
10 Mar
2026

Confirmation statement due

Confirmation Due

Next confirmation statement due date

30 Sep
2025

Accounts due

Accounts Due

Next accounts due date

25 Feb
2025

Confirmation Statement With Updates

Confirmation-statement

CS01 | Transaction MzQ1NjI4NjQ4NWFkaXF6a2N4

Published 25 Feb 2025 06:37

24 Feb
2025

Confirmation statement filed

Confirmation

Last confirmation statement made up date

20 Feb
2025

Certificate Change Of Name Company

Change-of-name

CERTNM | Transaction MzQ1NTgyMzg1NGFkaXF6a2N4

Published 20 Feb 2025 01:11

07 Oct
2024

Resolution

Resolution

RESOLUTIONS | Transaction WURDVUZPMUthZGlxemtjeA | Paper/PDF filed

Published 08 Oct 2024 06:28

01 Oct
2024

Capital Allotment Shares

Capital

SH01 | Transaction MzQzNzk4NTk5M2FkaXF6a2N4

Published 01 Oct 2024 03:49

17 Sep
2024

Resolution

Resolution

RESOLUTIONS | Transaction WURCSEpUWlZhZGlxemtjeA | Paper/PDF filed

Published 18 Sep 2024 07:11

10 Sep
2024

Appoint Person Director Company With Name Date

Officers

AP01 | Transaction MzQzNTA3NjYwMGFkaXF6a2N4

Published 10 Sep 2024 10:32

31 Dec
2023

Accounts filed

Accounts

Last accounts made up date

24 Feb
2010

Incorporated

Inception

Company registered at Companies House

Spinout profile

5 entries

Company description

Sphere Bio develops microfluidic cell and molecule screening technology with applications in cellular research, biopharmaceutical production, and diagnostics.

Sphere Fluidics develops microfluidic cell and molecule screening technology with applications in cellular research, biopharmaceutical production, and diagnostics.

Sphere Fluidics Limited is an established Life Sciences company which has developed unique products for use in single cell analysis and characterisation and provides collaborative Research and Development services in this area.

Project impact

Sphere Fluidics is one of the very few teams in the world with expertise in single cell analysis and pico droplet technology. The company has leading-edge, patented technology and proprietary know-how enables analysis and detection of single cells and their biomolecules. Sphere Fluidics has extensive management experience in successfully commercialising innovative science and engineering. Its expertise in new science with key applications has particular impact for novel biopharmaceutical and biosimilar discovery. Sphere Fluidics' novel process for single cell analysis and characterisation provides significant saving of time, resource and money compared to conventional workflows.

Sphere Fluidics
2010
Sphere Fluidics Limited
2010

Public funding

9 awards
First funded
2014
Funded years
2014, 2015, 2017, 2020, 2023, 2024
Age at first award
4 years

Projects

2024 Knowledge Transfer Partnership

University of Glasgow and Sphere Fluidics Limited KTP22_23 R5

25 Jan 2024 to 25 Jan 2026

Awarded
£0
Total cost £0

To embed expertise in injection moulding for rapid prototyping of hard plastic microfluidics; expanding in-house manufacturing capabilities to produce plastic biochips, thereby, bringing products to market faster, at lower cost and higher quality than competitors.

2023 Collaborative R&D Lead participant

Quality Control Test Efficiency

1 Mar 2023 to 31 Aug 2023

Awarded
£32,999
Total cost £54,998

Sphere Fluidics Limited is an established Life Sciences company based in Cambridge, UK. We provide tools for biopharmaceutical organisations which include instruments and cartridges based on novel microfluidics. This project addresses the speed and efficiency of a critical quality control test which is required to validate the Cyto-Mine single cell analys...

2023 EU-Funded Lead participant

3D spheroids derived from single cells for discovering stochastic patterns behind metastasis

1 Jan 2023 to 31 Dec 2026

Awarded
£701,677
Total cost £701,677

no public description

2020 Knowledge Transfer Partnership

Heriot-Watt University and Sphere Fluidics Limited

1 Jul 2020 to 30 Jun 2022

Awarded
Unknown

To develop a commercial instrument (PISCES-2) to allow high-throughput, monodisperse microdroplet generation.

2017 EU-Funded Lead participant

Precision Docking of Very Large DNA Cargos in Genomes

1 Oct 2017 to 30 Apr 2020

Awarded
£307,713
Total cost £539,657

Awaiting Public Project Summary

2017 Collaborative R&D Lead participant

Disrupting the global market for high value, gene-edited cell products and services with microfluidic technology

1 Jul 2017 to 31 Oct 2020

Awarded
£404,401
Total cost £577,715

Genetic engineering (GE) is an established tool for R&D and promises to become a globally used approach to correct and treat important diseases, such as cancer and genetic disease, and also able to tackle and solve important environmental issues. Current approaches are dependent upon manual labour and extensive screening, and are highly inefficient and ti...

2015 Collaborative R&D Lead participant

miFACTS: Microfluidic system for Flexible Automated Cell Transduction and Selection

1 Oct 2015 to 30 Sep 2018

Awarded
£339,556
Total cost £565,928

Cell therapy promises to become a globally used approach to treat important diseases, such as cancer. Current regimes can involve removing a patient's white blood cells (e.g. T-cells), reprogramming them to fight cancer and then reintroducing them to the patient. Current cellular reprogramming techniques are very inefficient (e.g. as low as 3%) and involv...

2014 Collaborative R&D Lead participant

A High Throughput Miniaturised Mass Spectrometry Tool for Profiling Synthetic Design Libraries

1 Oct 2014 to 31 Mar 2016

Awarded
£139,550
Total cost £232,584

Synthetic biology has advanced genetic manipulation by applying engineering principles (Design-Build-Test) to enable new discoveries by modifying safe microbes with custom DNA. The ability to write DNA has accelerated, but synthetic biology is now limited by a lack of high-throughput measurement methods to assess performance of custom-built strains. The p...

2014 Collaborative R&D Lead participant

A novel, single cell characterisation, dispensing and imaging platform for accelerated biopharmaceutical development

1 Jun 2014 to 30 Nov 2015

Awarded
£191,866
Total cost £319,776

Sphere Fluidics Limited is an SME focusing on the development of novel, single cell analysis technologies. MedImmune, the global biopharmaceuticals arm of AstraZeneca, is a pioneer in biopharmaceutical discovery and development. Both companies have pooled their synergistic, science skills to propose the development of a unique, integrated microfluidic ins...

Product types

Collaborative R&D EU-Funded Knowledge Transfer Partnership