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Company profile

Lightox Limited

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Illuminating therapeutics & research tools. LightOx are developing new therapeutic solutions to improve patients function and long-term outcomes with oral cancer. We have a unique range of molecular tools for use in imaging, therapeutics and assay development.

CRN
10308130
Founded
2016
Age
9

Overview

Browse spinouts
Legal name
LIGHTOX LIMITED
Region
Unknown
Registered address
C/O MENZIES LLP ONE EXPRESS
1 GEORGE LEIGH STREET
MANCHESTER
GREATER MANCHESTER
ENGLAND
M4 5DL
Insolvency history
No

Company events

Reference milestones and recent Companies House filing stream events.

8 events
31 May
2027

Accounts due

Accounts Due

Next accounts due date

15 Aug
2026

Confirmation statement due

Confirmation Due

Next confirmation statement due date

31 Aug
2025

Accounts filed

Accounts

Last accounts made up date

01 Aug
2025

Confirmation statement filed

Confirmation

Last confirmation statement made up date

20 Aug
2024

Confirmation Statement With Updates

Confirmation-statement

CS01 | Transaction MzQzMjc3MTAwOGFkaXF6a2N4

Published 20 Aug 2024 15:28

20 Aug
2024

Notification Of A Person With Significant Control Statement

Persons-with-significant-control

PSC08 | Transaction MzQzMjc2NzQwNmFkaXF6a2N4

Published 20 Aug 2024 14:55

20 Aug
2024

Cessation Of A Person With Significant Control

Persons-with-significant-control

PSC07 | Transaction MzQzMjc2Njg3MGFkaXF6a2N4

Published 20 Aug 2024 14:50

02 Aug
2016

Incorporated

Inception

Company registered at Companies House

Spinout profile

3 entries

Company description

LightOx develops light activated chemotherapy designed to treat early-stage oral cancer, with its technology also having applications as a research tool in imaging, therapeutics and assay binding.

Project impact

2 Patents

None

LightOx
2016
LightOx
2016
LightOx
2016

Public funding

7 awards
First funded
2019
Funded years
2019, 2020, 2022, 2023, 2024
Age at first award
3 years

Projects

2024 Collaborative R&D Lead participant

Light-activated antimicrobials for wound care

1 May 2024 to 31 Oct 2025

Awarded
£297,479
Total cost £424,970

The management of wounds is a "silent epidemic" that is challenging health services worldwide. The NHS treated 3.8 million patients with a wound in 2017/18, translating to a burden of \>£8.3billion. A major factor that influences the successful healing of a wound is an infection by colonising microbes. Untreated infections prevent healing, but can also sp...

2024 Collaborative R&D Lead participant

Customer discovery and market access planning for light-activated antimicrobial wound care product

1 Apr 2024 to 31 Mar 2025

Awarded
£99,993
Total cost £99,993

The management of wounds is a "silent epidemic" that is challenging health services worldwide. The NHS treats 2.2 million patients with a chronic wound, the management of which costs at least £5.6 billion each year. A major factor inhibiting wound healing is infections caused by colonising microbes. Untreated infections prevent healing and often spread; t...

2023 Collaborative R&D Lead participant

Light-activated wound sterilisation prototype development

1 Dec 2023 to 31 May 2025

Awarded
£239,103
Total cost £341,575

The management of wounds is a "silent epidemic" that is challenging health services worldwide. The NHS treated 3.8 million patients with a wound in 2017/18, translating to a burden of \>£8.3billion. A major factor that influences the healing of a wound is an infection by colonising microbes. Untreated infections prevent healing, but can also spread furthe...

2023 Collaborative R&D Lead participant

Light-activated therapy for oral epithelial dysplasia

1 May 2023 to 30 Apr 2025

Awarded
£677,132
Total cost £967,332

Oral cancers are the 14th most common cancer in the UK. Around 50% of patients die within 5-years of diagnosis, whilst a reliance on invasive surgery (used in 95% of cases) means that survivors are left with severe life-long impacts affecting swallowing, eating and speech. The number of cases of oral cancer is increasing, particularly in those aged 50+, w...

2023 Collaborative R&D Lead participant

Advanced characterisation of imaging probe products

1 Mar 2023 to 31 Aug 2023

Awarded
£14,749
Total cost £24,581

LightOx are a drug development company based in Newcastle upon Tyne that has made its light-activated products, known as LightOx Probes, available to other researchers to enable them to understand biological processes that occur in a cell. LightOx has shown that their Probe molecules are capable of emitting fluorescence when they are activated by light, a...

2022 Collaborative R&D Lead participant

Need for 2 photon measurements to demonstrate advanced capability of LightOx probes and inform new probe development

1 Jan 2022 to 31 Mar 2022

Awarded
£14,022
Total cost £14,022

LightOx are a drug development company based in the North East of England that has made its light-activated products available to other researchers to develop and understand the biological processes that occur in a cell. These "LightOx Probes" act to show biological researchers the importance of specific cell functions and the mechanisms that cells use to...

2020 Feasibility Studies Lead participant

Expanding LightOx Probes capability through analytical methodologies and analysis to broaden customer base.

1 Jun 2020 to 30 Nov 2020

Awarded
£52,027
Total cost £52,027

no public description

2019 Collaborative R&D Lead participant

Expanding LightOx Probes capability through analytical methodologies and analysis to broaden customer base.

1 Dec 2019 to 30 Jun 2021

Awarded
£29,122
Total cost £41,603

LightOx looks to advance the scientific field of biological imaging using fluorescence by developing novel agents that have intrinsic chemical properties for targeting cell subtypes and intracellular organelles. The experimental basis of this comes from a background of 15 years of research within university institutes and are now being undertaken by the c...

Product types

Collaborative R&D Feasibility Studies